The Board Of Trustees Of The University Of the Leland Stanford Junior University;Benaroya Research Institute at Virginia Mason
发明人:
申请号：
EP14836423.5
公开号：
EP3033416A4
申请日:
2014.08.12
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Compositions for treating autoimmune, allergic, or atopic disease comprising a compound that inhibits hyaluronan synthesis and a pharmaceutically acceptable carrier are described. In some embodiments, the compound that inhibits hyaluronan synthesis is 4-methylumbelliferone or a metabolite of 4-methylumbelliferone. Methods for treating autoimmune diabetes, multiple sclerosis and/or autoimmune demyelination, including administering to the subject a composition having a compound in an amount effective to inhibit hyaluronan synthesis in a mammalian subject, are also described.
