The present invention provides a liquid antiseptic composition including (A) parahydroxybenzoic acid ester and (B) water-miscible organic solvent, wherein the (A) parahydroxybenzoic acid ester are two or more esters selected from the group consisting of methyl parahydroxybenzoate, ethyl parahydroxybenzoate, propyl parahydroxybenzoate, isopropyl parahydroxybenzoate, butyl parahydroxybenzoate, isobutyl parahydroxybenzoate and benzyl parahydroxybenzoate; the (B) water-miscible organic solvent contains (B-1) at least one organic solvent selected from the group consisting of propylene glycol, butylene glycol, ethanol and polyethylene glycol, and (B-2) 2-phenoxyethanol; and a weight ratio of (A) and (B) is 1:1 to 1:3, and a weight ratio of (B-1) and (B-2) is 1:1 to 1:3.本發明提供液態抗菌組成物,該液態抗菌組成物包含(A)對羥基苯甲酸酯及(B)水混溶性有機溶劑,其中,(A)對羥基苯甲酸酯為2種或多種選自下列者所組成之群組的酯類:對羥基苯甲酸甲酯、對羥基苯甲酸乙酯、對羥基苯甲酸丙酯、對羥基苯甲酸異丙酯、對羥基苯甲酸丁酯、對羥基苯甲酸異丁酯及對羥基苯甲酸苯甲酯;(B)水混溶性有機溶劑含有(B-1)至少一種選自丙二醇、丁二醇、乙醇及聚乙二醇所組成之群組的有機溶劑,及(B-2)2-苯氧基乙醇;且(A)與(B)的重量比為1:1至1:3,及(B-1)與(B-2)的重量比為1:1至1:3。