KIM JIN-SUN;JANG MYUNG HYUN;LEE SANG HYUN;SUNG YOUB JUNG;IN YOUNG CHOI;HANMI PHARM. CO. LTD.;KWON SE CHANG
发明人:
SUNG YOUB JUNG,IN YOUNG CHOI,KWON SE CHANG,KIM JIN-SUN,JANG MYUNG HYUN,LEE SANG HYUN
申请号：
IL23691315
公开号：
IL236913D0
申请日:
2015.01.25
申请国别(地区):
IL
年份:
2015
代理人:
摘要：
The present invention relates to a composition for preventing or treating hyperlipidemia, fatty liver disease or arteriosclerosis, comprising an oxyntomodulin derivative as an active ingredient. The oxyntomodulin derivative has a high ability to activate GLP-1 receptor and glucagon receptor compared to native oxyntomodulin and has the effects of reducing the blood total cholesterol, low-density cholesterol and triglyceride levels that were increased by high-fat diet, and increasing high-density cholesterol levels and the high-density cholesterol/low-density cholesterol ratio. Thus, the oxyntomodulin derivative can be effectively used for the treatment of hyperlipidemia and related diseases.
