Ryan W. Chau,Courtney A. Cullis,Matthew O. Duffey,Krista E. Gipson,Yongbo Hu,Gang Li,Michael D. Sintchak,Tricia J. Vos
申请号:
US13721877
公开号:
US20130165472A1
申请日:
2012.12.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention provides compounds of formula IA:and also provides compounds of formula IIA, IIIA, IVA, or VA:wherein HY, R1, R2, R3, R14, G1, G2, G3, and G4, are as described in the specification. The compounds are inhibitors of VPS34 and/or PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.