The invention concerns a mixture of enzymes from krill for use in the treatment of a soft tissue including epithelial tissue and mucosa on which soft tissue a biofilm has formed or is expected to form, which soft tissue is a soft tissue of a mammal and which treatment comprises the removal of the biofilm or preventing a formation of the biofilm.Linvention concerne un mélange denzymes de krill pour utilisation dans le traitement dun tissu mou comprenant un tissu épithélial et une muqueuse, tissu mou sur lequel un biofilm sest formé ou pourrait se former, ledit tissu mou étant un tissu mou dun mammifère et ledit traitement comprenant lélimination du biofilm ou la prévention de la formation du biofilm.