Richard I. HOGREFE,Alexandre LEBEDEV,Anton P. MCCAFFREY,Dongwon SHIN
申请号:
US16371317
公开号:
US20190270766A1
申请日:
2019.04.01
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided herein are methods and compositions for synthesizing 5′;Capped RNAs wherein the initiating capped oligonucleotide primers have the general form m7Gppp[N2′;Ome]n[N]m wherein m7G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.