Formulations Preserving Bioactivity and Methods of Their Preparation

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专利权人:

Per Wikström

发明人:

Per Wikström,Tobias Bramer,Lilyan Yachoh

申请号：

US13701579

公开号：

US20130156858A1

申请日:

2011.05.30

申请国别(地区):

US

年份:

2013

代理人:

摘要：

A pharmaceutical composition comprising an alginate hydrogel core where a bioactive agent is entrapped. The water content of the hydrogel is at least 10% of equilibrium water content. The beads have an enteric coating and are intended for oral administration. The bioactive agent is bioactive proteins, antibodies or viable cells and it is intended to exert its activity in the duodenum and the upper intestines.

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