Disclosed is a medical drug delivery device, comprising an ultrasonic generator (4) and a cavity body (1), wherein the cavity body (1) can be pressed closely against human skin and has a liquid permeation structure set in the side, and an ultrasonic transducer (2) is arranged inside the cavity body (1) with the ultrasonic transducer (2) being electrically connected to the ultrasonic generator (4) through a wire (3), and the cavity body (1) is in communication with a drug delivery tube (7) with a bleeder pipe being set in the cavity body (1), and the drug delivery tube (7) is connected to a liquid medicine storage pump (6). The ultrasonic transducer (2) is an ultrasonic piezoelectric ceramic piece, and the drug delivery device also comprises a controller (5) connected to a computer, and the liquid medicine storage pump (6) and ultrasonic generator (4) are controlled by the controller (5). A pressure testing probe (11), which is connected to the controller (5), is arranged in the liquid medicine after being outputted by the liquid medicine storage pump (6). The medical drug delivery device does not need to break the skin using a needle to perform drug delivery, causes no trauma, can reduce patients pain and chances of infection, and increases the drug sensitivity of human cells, thereby improving the therapeutic effects.Linvention concerne un dispositif médical dadministration de médicaments, comprenant un générateur ultrasonique (4) et un corps de cavité (1), le corps de cavité (1) pouvant être pressé étroitement contre la peau humaine et présentant une structure de perméation de liquide placée dans le côté, et un transducteur ultrasonique (2) étant agencé à lintérieur du corps de cavité (1), le transducteur ultrasonique (2) étant connecté électriquement au générateur ultrasonique (4) via un fil (3) et le corps de cavité (1) étant en communication avec un tube dadministration de médicament (7) présentant un tube de purge placé dans le corps de cavité (1) et le tube d