An aqueous contact lens solution comprising less than 100 ppm of a tertiary amine oxide of general formulawherein R1 is a C8-C18alkyl, and R2 and R3 are independently selected from a C1-C4alkyl or C1-C4hydroxyalkyl, and an antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds, hydrogen peroxide or a stabilized form of peroxide and any one mixture thereof. The solution has no anionic surfactant or less than 30 ppm of anionic surfactant. The invention is also directed to the use of the solution to clean and disinfect contact lenses, and in particular, soft, silicone, hydrogel contact lenses.
