Nak Jeong Kim,Myung-Ae Bae,Sung-Eun Yoo,Namsook Kang,Jung Nyoung Heo,Kyu Yang Yi,Jee Hee Suh,Sung Youn Chang,Eun Sook Hwang,Jeong-Ho Hong
申请号：
US13734348
公开号：
US09090608B2
申请日:
2013.01.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A pharmaceutical composition comprising a phenyltetrazole derivative of formula (I) or a pharmaceutical acceptable salt thereof is effective in preventing or treating osteoporosis, obesity, diabetes, or hyperlipidemia, by regulating protein TAZ.wherein, A is ethyl or n-butyl； R1 is methyl, —CH2OH, —CO2CH3, —CH2F, —CH(OCH3)2, —CH2OC(═O)CH3, styryl or —CH2OCH2SCH3； R2 is H, Br, —CO2CH3, phenyl, pyridin-2-yl, pyridin-3-yl,or styryl； R3 is H or methyl； X is CH or N； and P is H or —CH(CH3)OCH2CH3.
