SIBLEY GRAHAM EDWARD MORRIS,LAW DEREK,OLIVER JASON DAVID,BIRCH MICHAEL
申请号：
IN201717017445
公开号：
IN201717017445A
申请日:
2017.05.18
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The invention provides a pyrrole compound which compound is (a)2 (1 5 dimethyl 3 phenyl 1H pyrrol 2 yl) N (4 (4 (5 fluoropyrimidin 2 yl)piperazin 1 yl)phenyl) 2 oxoacetamideor a deuterated derivative thereof or(b)2 (1 5 dimethyl 3 phenyl 1H pyrrol 2 yl) N (4 (4 (5 fluoropyrimidin 2 yl)piperazin 1 yl) 3 hydroxyphenyl) 2 oxoacetamide or a deuterated derivative thereof or (c) a prodrug of compound (a) or a prodrug of compound (b) or a pharmaceutically acceptable salt or agriculturally acceptable salt of (a) (b) or (c). Also provided are combinations and compositions comprising the compound and known antifungal agents. The invention also relates to the therapeutic use of a compound of the invention in prevention or treatment of fungal diseases. It also relates to the use of:2 (1 5 dimethyl 3 phenyl 1H pyrrol 2 yl) N (4 (4 (5 fluoropyrimidin 2 yl)piperazin 1 yl)phenyl) 2 oxoacetamide or an agriculturally acceptable salt thereof or 2 (1 5 dimethyl 3 phenyl 1H pyrrol 2 yl) N (4 (4 (5 fluoropyrimidin 2 yl)piperazin 1 yl) 3 hydroxyphenyl) 2 oxoacetamide or an agriculturally acceptable salt thereof as an agricultural fungicide.
