One aspect of the present disclosure relates to a device for aspirating a biological tissue from a subject. The device can comprise a flexible, hollow shaft and an ultrasound assembly. The shaft can have a central portion that extends between a proximal end and a distal end thereof. The shaft can include a first lumen that extends between the proximal and distal ends. The ultrasound assembly can be connected to the distal end of the shaft. The ultrasound assembly can include a casing, at least one ultrasound transducer disposed within the casing, and a second lumen that extends through the ultrasound assembly and is in fluid communication with the first lumen. The at least one ultrasound transducer can be configured to generate acoustical waves having an intensity and frequency sufficient to disrupt, but not substantially damage, the biological tissue so that the biological tissue can be aspirated through the device.
