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PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2-(TETRAHYDRO-PYRAN-4-YLAMINO)-BENZAMIDE
专利权人:
NERVIANO MEDICAL SCIENCES S.R.L.
发明人:
Natale Alvaro Barbugian,Romualdo Forino,Tiziano Fumagalli,Paolo Orsini
申请号:
US15172478
公开号:
US20160279125A1
申请日:
2016.06.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a process for the preparation of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide. Novel solid forms of this compound, their utility in treating diseases caused by deregulated protein kinase activity and pharmaceutical compositions containing them are also object of the present invention.
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