PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZOL-3-YL]-4-(4-METHYL-PIPERAZIN-1-YL)-2-(TETRAHYDRO-PYRAN-4-YLAMINO)-BENZAMIDE

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专利权人:

NERVIANO MEDICAL SCIENCES S.R.L.

发明人:

Natale Alvaro Barbugian,Romualdo Forino,Tiziano Fumagalli,Paolo Orsini

申请号：

US15172478

公开号：

US20160279125A1

申请日:

2016.06.03

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention relates to a process for the preparation of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide. Novel solid forms of this compound, their utility in treating diseases caused by deregulated protein kinase activity and pharmaceutical compositions containing them are also object of the present invention.

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