Pyridin-4-yl substituted 2-carboxamide pyrrolidine-amide urea derivatives and their use in the treatment of phosphatidylinositol 3-kinase mediated diseases
CARAVATTI, GIORGIO,FAIRHURST, ROBIN ALEC,FURET, PASCAL,GUAGNANO, VITO,IMBACH, PATRICIA
申请号:
NZ59075409
公开号:
NZ590754A
申请日:
2009.09.08
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Provided are pyridin-4-yl substituted 2-carboxamide pyrrolidine-amide urea derivatives of the depicted formula, with defined substituents, limited to a pyridine substituent at the position of ring A in the proline-amide thiazole compound. The compounds are useful in the treatment of phosphatidylinositol 3-kinase mediated diseases, including various cancers.