The United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
James Noble Kochenderfer
申请号：
US14389677
公开号：
US09765342B2
申请日:
2013.03.15
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.
