A sealing perforable closing device is associable to a medical apparatus provided with a housing for said device (1) and engageable by a needle along a piercing direction. Said device (1) comprises a body means (2) comprising an absorbent material (6) of liquids. In an operative condition of extraction of the needle, possible liquids contacting the absorbent material are absorbed and they cause the increasing of volume of the material the same and of the body means (2) that expanding itself seals the perforation crossing the body means (2).
