Yuxi Pang,Thomas L. Chenevert,Riann Palmieri-Smith
申请号：
US16385981
公开号：
US20190313936A1
申请日:
2019.04.16
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Technology for measuring clinically relevant Magnetic Resonance (MR) anisotropic water proton transverse relaxation rates of cartilage in human knees and other joints is provided. A single sagittal T2-weighted magnetic resonance image of a cartilage associated with a human knee or other joint may be acquired, and an internal reference signal may be measured from this acquired sagittal image. The internal reference signal is a signal intensity (S(θ))from the cartilage with its collagen fiber orientated approximately 54.7° to the main magnetic field. An anisotropic R2 relaxation rate (R(θ)2a) may be calculated for the cartilage using the following equation: R(θ)2a={log(S(θ=±54.7°))−；log(S(θ))}/TE. Accordingly, an indication of a degeneration of the cartilage may be determined using the calculated anisotropic R2 relaxation rate.
