The Board of Regents of the University of Oklahoma
发明人:
Paul L. DEANGELIS,Rachel S. LANE
申请号：
US14921732
公开号：
US20160114050A1
申请日:
2015.10.23
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compositions, methods, and systems are disclosed for the development and use of heparosan, a natural polymer related to heparin, as a new therapeutic modifying agent or complexation vehicle which can modulate drug cargo pharmacokinetics and behavior within a mammalian patient. In certain non-limiting embodiments, the use of heparosan is complexed with anti-cancer drugs and the like, thus forming a prodrug for the purposes of increasing efficacy and reducing side effects compared to the parental drug alone.
