This Hair is bright be related to comprising N- 3- [the iodo- phenyl amino of the 3- fluoro- 4- of Ring propyl -5-(2-) -6,Dimethyl -2 8-,4,Trioxy- -3 7-,4,6,Tetra- Hydrogen -2H- pyrido of 7- [4,3-d] pyrimidine -1- base] phenyl } the molten Elixirs of acetamide dimethyl Asia Sulfone closes the Drug Wu Group of object and closes object, using The Group closes the method Yi of object Ji the method that System Prepare The Group closes object in controlling Treatment.本發明涉及包含N-{3-[3-環丙基-5-(2-氟-4-碘-苯基氨基)-6,8-二甲基-2,4,7-三氧代-3,4,6,7-四氫-2H-吡啶并[4,3-d]嘧啶-1-基]苯基}乙酰胺二甲基亞碸溶劑合物的藥物組合物、在治療中使用該組合物的方法以及製備該組合物的方法。