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FILMS FOR DELIVERING PHOTODYNAMIC THERAPEUTIC DRUGS
专利权人:
TAIPEI MEDICAL UNIVERSITY
发明人:
TSAI, TSUI MIN,蔡翠敏,蔡翠敏
申请号:
TW102148997
公开号:
TWI515023B
申请日:
2013.12.30
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
Disclosed herein are films for delivering a photodynamic therapeutic drug. The film for delivering a photodynamic therapeutic drug has a polymeric matrix and the photodynamic therapeutic drug dispersed within the polymeric matrix. The photodynamic therapeutic drug is 5-aminolevulinic acid or a pharmaceutically acceptable salt thereof. In one embodiment, the polymeric matrix has a dry weight of about 0.45-4.7 parts by weight and consists of 0.4-4 parts by weight of a polyoxyethylene-polyoxypropylene- polyoxyethylene copolymer, 0.02-0.2 parts by weight of a poly(acrylic acid) crosslinked with divinyl glycol, 0.03-0.5 parts by weight of a cellulose derivative, and water all based on one part by weight of the photodynamic therapeutic drug.在此揭示光動力療法藥物之遞送薄膜,此光動力療法藥物之遞送薄膜有一聚合物基質,且光動力療法藥物係分散於該聚合物基質中。該光動力療法藥物為5-胺基酮戊酸或其藥學上可接受鹽類。於一實施例中,聚合物基質的乾重為約0.45-4.7重量份;且其係由0.4-4重量份的聚氧乙烯-聚氧丙烯-聚氧乙烯共聚物、0.02-0.2重量份的丙烯酸與二乙烯乙二醇交聯之聚合物、0.03-0.5重量份的纖維素衍生物以及水所組成;以上皆以1重量份的光動力療法藥物為基準。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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