Duane D. Miller,Wei Li,Zhao Wang,Yan Lu,Jianjun Chen,James T. Dalton,Chien-Ming Li
申请号:
US12485881
公开号:
US08592465B2
申请日:
2009.06.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds according to formula (I) are disclosedwhere Q is S, N, or O X is optional, and can be O═, S═, ═N—NH2, ═N—OH, or —OH Y is optional and can be —N(H)—, O, or C1 to C20 hydrocarbon and R1 and R2 are each independently substituted or unsubstituted single-, fused- or multiple-ring aryl or (hetero)cyclic ring systems. Methods of making these compounds, pharmaceutical compositions containing the compounds, and their use, particularly for treating or preventing cancer, are also disclosed.