An inverted battery device has a pair of electrodes, first and second volumes, and an electrical conductor. One of the pair of electrodes is configured as an anode and the other is configured as a cathode. A first electrolyte solution and the anode are disposed in the first volume, while a second electrolyte solution and the cathode are disposed in the second volume. The electrical conductor extends between the first and second volumes to couple the pair of electrodes to each other such that electrons travel between the pair of electrodes. The device is constructed to produce ions rather than electrons such that an ionic current can be generated in a separate system, such as a biological system or other ionic system, when coupled between the anode and cathode.