Tucker Curran Roberts,Peter Andrew Smith,Robert I. Higuchi,David Campbell,Prasuna Paraselli
申请号:
US14086908
公开号:
US09309285B2
申请日:
2013.11.21
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.