Apoptosis related protein in the tgf-beta signaling pathway (arts) mimetic compounds, compositions, methods and uses thereof in induction of differentiation and/or apoptosis of premalignant and malignant cells, thereby restoring their normal-like phenoty

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专利权人:

Carmel-Haifa University Economic Corporation Ltd.

发明人:

申请号：

IL25905118

公开号：

IL259051D0

申请日:

2018.04.30

申请国别(地区):

IL

年份:

2018

代理人:

摘要：

Provided are ARTS mimetic compounds that act as novel antagonists for XIAP and Bcl-2. Further, the novel ARTS mimetic compounds of the presently claimed subject matter induce apoptosis and/or differentiation in premalignant and malignant cells and thereby restore their normal-like phenotype. Further provided are compositions, methods and uses of said ARTS mimetic compounds in the treatment of cancer and premalignant conditions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/