Useful compounds for inhibition of replication of respiratory synchronous virus (VSR)It also relates to the preparation of these compounds, including the components of these compounds and compounds for the treatment of respiratory octylvirus infection. 1. Claim 1: a formula compound (1),Or a stereoisomerization form of it, in which het is a different formula period (2),(3)(4) (5)each X independently is C or N； provided that at least one X is N； R¹ᵇ is present when Het has the formula (2) and X is C； each R¹ᵇ is independently selected from the group consisting of H, halogen, C₁₋₆ alkyl,C₃₋₇ cycloalkyl,C₁₋₆ alkyloxy,N (R)CO (R)CH₂NH₂,Ch8322； Oh, CN, C (= Noh) nh832222；C (NOCH) NHC (3DNF) NHCF8323,OCF83223,B (OH) ₂ and B (O-C₁₋₆ alkyl) ₂；R1 749595 is absent, if x is connected with N； R2 7495es - (cr.8322； r831393) - 8344； - r8304； - 74955；Each r83100s is selected independently from group H, lease agreement No. c83218c83312626；Cooch83323 and conhso 83222； ch832323；each R⁷ is independently selected from the group consisting of OH, C₁₋₆ alkyloxy,NH.8322；NHSO N (alquil C)NHSO₂NHCH₃,NHSO₂ (C₁₋₆ alkyl),NHSO₂ (C₃₋₇ cycloalkyl) and N (C₁₋₆ alkyl) ₂；each of R⁸ and R⁹ is independently selected from the group consisting of H, C₁₋₁₀ alkyl and C₃₋₇ cycloalkyl；O r831222 and r8313 together form a crystal circle composed of 4 to 6 members, optionally containing one or more heteroatoms selected from groups n, s and O； r83044； 74955 selected from group H, R1,OH CN F CF H CFCONR⁸R⁹,Coordination 831222,CON (R) SO RCON (R) SO N (R R)8312； 8313；No. 831222； coordination No. 8313；OCOR⁸,O-benzene, No. 831222； so8322； r8313；SO NR RSO₂R⁸,8312； 8313；Directive 831222； R1,N (R) CON (R R)N (R) COORand a saturated ring of 4 to 6 members containing an oxygen atom； m is an integer between 2 and 6； R¹¹ is selected from the group consisting of C₁₋₆ alkyl,C₃₋₇ cycloalkyl,e. Phenyl, pyridyldi and pyrazolate； each substitute is replaced by one or more substitutes selected by a team composed of cf832323；Ch83
