John G. Devane,Paul Stark,Niall M.M. Fanning,Gurvinder Singh Rekhi,Scott A. Jenkins,Gary Liversidge
申请号:
US15193514
公开号:
US20170000783A1
申请日:
2016.06.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to a multiparticulate modified release composition that, upon administration to a patient, delivers at least one active ingredient in a bimodal or multimodal manner. The multiparticulate modified release composition comprises a first component and at least one subsequent component the first component comprising a first population of active ingredient containing particles and the at least one subsequent component comprising a second population of active ingredient containing particles wherein the combination of the components exhibit a bimodal or multimodal release profile. The invention also relates to a solid oral dosage form containing such a multiparticulate modified release composition.