Compositions and methods of use of PD-1 antagonists

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专利权人:

アンプリミューン、インコーポレーテッド

发明人:

ソロモン、ランガーマン,リンダ、リウ

申请号：

JP2011524986

公开号：

JP5798919B2

申请日:

2009.08.25

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

Methods of treating cancer and infectious diseases utilizing a treatment regimen comprising administering a compound that reduces inhibitory signal transduction in T cells, in combination with a potentiating agent, such a cyclophosphamide, to produce potent T cell mediated responses, are described. Compositions comprising the PD-1 antagonists and potentiating agents useful in the methods of the invention are also disclosed.

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中国工程科技知识中心

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http://www.ckcest.cn/home/