FIELD: medicine； pharmaceuticals.SUBSTANCE: present invention refers to pharmaceutical industry, namely to a method for producing stable nanosuspension. Disclosed is a method of producing a stable nanosuspension containing at least one natural material, the method comprising the steps of: providing at least one natural material in which 100 % of the volume of particles has a particle size of less than 320 mcm； dispersing said at least one natural material in a solvent； milling the dispersion such that 90 % of the volume of the particles has a particle size of less than 500 nm (D90<；500 nm), wherein the dispersion step or the grinding step includes adding a stabilizer, wherein at least one natural material is selected from a group consisting of plants, cyanobacteria, algae and fungi, and the natural material does not contain ginseng. Disclosed is nanosuspension for preparing a drug. Nanosuspension for treating or preventing a disease selected from cancer and inflammatory bowel disease, in which at least one natural material is a Brazilian agaricus (agaricus subrufescens), wherein concentration of Brazilian agar in nanosuspension is 5 % wt/wt. Application of nanosuspension for preparing a drug. Use of nanosuspension for preparing a drug for treating or preventing a disease specified in cancer and inflammatory bowel disease.EFFECT: above-described suspension is stable and effective for treating or preventing a disease specified in cancer and inflammatory bowel disease.40 cl, 22 dwg, 13 exНастоящее изобретение относится к фармацевтической промышленности, а именно к способу получения стабильной наносуспензии. Представлен способ получения стабильной наносуспензии, содержащей по меньшей мере один природный материал, при этом способ включает стадии: предоставление по меньшей мере одного природного материала, в котором 100% объема частиц имеет размер частиц менее 320 мкм； диспергирование указанного по меньшей мере одного природного материала в растворителе； измельчение дис
