Miha Vrbinc,Berta Kotar-Jordan,Rok Zupet,Matej J. Smrkolj
申请号:
US13346931
公开号:
US20120283291A1
申请日:
2012.01.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to a solid pharmaceutical composition comprising donepezil hydrochloride hydrate and a process for its preparation. In particular it relates to a composition and a process wherein the donepezil hydrochloride retains its polymorphic form and is therefore highly stable against conversion into other polymorphic forms.