An infusion filter design combines a fluid infusion device and a blood filtration device that filter blood during a thrombolysis procedure while allowing for complete filter removal on procedure completion. In one embodiment, a wire comprises a proximal, non-infusible length that extends partially outside of the patient and within the vein. The wire further comprises an infusible length distally from the non-infusible length that is extends within the vein so as to be placed at the section of the vein requiring medication. The wire also comprises a distal filter component at a distal end of the wire that is employed to filter the blood in the event that during the period that clot is dissolved it migrates toward the central circulation.
