A method of in-situ adhering comprising providing pre-gel that comprises a mixture of at least one phenol-based compound and at least one water miscible polymer selected from at least one of a naturally existing form of a carbohydrate, a synthetically prepared form of carbohydrate and a salt of an anionic polysaccharide； spreading a layer of the pre-gel onto a first surface； adding a solid support, comprising at least one cross linking agent capable of interacting with the water miscible polymer to the pre-gel； and allowing the pre-gel to cure and adhere onto the first surface.
