噻唑衍生物及使用該衍生物作為ＶＡＰ－１抑制劑之用途农业专利-农业专业知识服务系统

发明人:: MATSUKAWA, TATSUYA,松川达也,松川達也,MASUZAKI, KAZUHIRO,增崎和浩,KAWAI, YOSUKE,河合阳介,河合陽介,KAWASAKI, AKIKO,川晶子,AKASAKA, AKIKO,赤坂阿希子,TAKEWAKI, MAKOTO,竹脇诚,竹脇誠

摘要：: The present invention provides a novel thiazole derivative useful as a VAP-1 inhibitor, a pharmaceutical agent for the prophylaxis or treatment of VAP-1 associated diseases and the like.A compound represented by the formula (I):Rl-NH-X-Y-Z　(I)wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.本發明提供一種有用於作為血管黏附蛋白質-1(vascular adhesion proteih-1,VAP-1)抑制劑、VAP-1相關疾病之預防或治療用醫藥劑等之新穎之噻唑(thiazole)衍生物。一種由式(I)所示之化合物或其醫藥上可接受之鹽：R1-NH-X-Y-Z　(I)式中，每個符號係如本案說明書中定義。