COMEAU, MICHAEL R.,SMOTHERS, JAMES F.,YOON, BO-RIN P.,MEHLIN, CHRISTOPHER
申请号：
MYPI 2010000985
公开号：
MY150242A
申请日:
2008.09.09
申请国别(地区):
MY
年份:
2013
代理人:
摘要：
THE PRESENT DISCLOSURE PROVIDES COMPOSITIONS AND METHODS RELATING TO ANTIGEN BINDING PROTEINS WHICH BIND TO HUMAN THYMIC STROMAL LYMPHOPOIETIN (TSLP), INCLUDING ANTIBODIES. IN PARTICULAR EMBODIMENTS, THE DISCLOSURE PROVIDES FULLY HUMAN, HUMANIZED AND CHIMERIC ANTI-TSLP ANTIBODIES AND DERIVATIVES OF SUCH ANTIBODIES. THE DISCLOSURE FURTHER PROVIDES NUCLEIC ACIDS ENCODING SUCH ANTIBODIES AND ANTIBODY FRAGMENTS AND DERIVATIVES, AND METHODS OF MAKING AND USING SUCH ANTIBODIES INCLUDING METHODS OF TREATING AND PREVENTING TSLP-RELATED INFLAMMATORY AND FIBROTIC DISORDERS.
