THE REGENTS OF THE UNIVERSITY OF COLORADO; A BODY CORPORATE
发明人:
SAUER, WILLIAM,NGUYEN, DUY
申请号：
CA3027520
公开号：
CA3027520A1
申请日:
2017.05.04
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The presently disclosed subject matter provides agents, compositions, and methods for augmenting ablation of a target tissue in a subject in need thereof, for example, using agents that modulate protective and/or reparative cellular processes induced in target tissue by application of ablative energy to the target tissue to sensitize the target tissue to the ablative energy. The presently disclosed subject matter further provides methods for augmenting radiofrequency ablation of cardiac tissue, for example, by applying radiofrequency energy to ablate cardiac tissue in the presence of metallic nanoparticles magnetically guided to the cardiac tissue.
