An isolated antibody that selectively binds to beta-amyloid peptide, a pharmaceutical composition comprising said antibody, nucleic acid sequence, vector and host cell
STEFAN EWERT,ADRIAN AUF DER MAUR,SUSAN CATTEPOEL,ROGER NITSCH
申请号：
BRPI0817099
公开号：
BRPI0817099A2
申请日:
2008.09.15
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The invention discloses an isolated antibody that selectively binds to the C-terminal part of Abeta and is humanized or fully human. The antibody of the invention is capable of preventing oligomerization of Abeta. Furthermore, a method of diagnosis comprising the steps of: (i) Labelling an antibody； (ii) Administering an effective dose of said antibody intranasally or systemically to a subject； and (iii) Detecting the concentration and/or presence of the labelled antibody in body parts of the subject is disclosed.
