An optical intervertebral implantation system can be used for a method of implanting an intervertebral implant into an intervertebral space with visualization. The system can include an elongate light guide and an intervertebral implant operably coupled with the elongate light guide. The elongate light guide can be configured as a guide wire and received through an aperture of the implant. The elongate light guide can be configured as a guide wire and the implant is received over and slides along on outside surface of the elongate light guide. The elongate light guide can be configured as a cannula having an internal conduit and the implant is received within the conduit. The elongate light guide can be configured as a cannula with an internal conduit and the implant is slidably coupled with an internal surface of the internal conduit of the cannula.
