Provided herein are antibodies that specifically bind to ERFE having variable heavy chain domains (VH), variable light chain domains (VL), and complementarity determining regions disclosed herein, as well as methods and uses in treating diseases and disorders of iron metabolism.本文提供特異性結合至ERFE之具有本文揭示之可變重鏈結構域(VH)、可變輕鏈結構域(VL)及互補決定區的抗體，以及治療鐵代謝之疾病及病症之方法及用途。
