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Lectin compositions and methods for modulating an immune response to an antigen
专利权人:
发明人:
Andrew H. Segal,Elihu Young
申请号:
US15345697
公开号:
US09951113B2
申请日:
2016.11.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a fusion polypeptide which can bind to a cell surface binding moiety (e.g., a carbohydrate) and serve as a ligand for a cell surface polypeptide, as well as a vector comprising a nucleic acid encoding for such a fusion polypeptide, and a host cell comprising such nucleic acid. The present invention also provides a composition comprising an antigen bearing target and such a fusion polypeptide, as well as a composition comprising a virus or a cell and such a fusion polypeptide. The present invention further relates to a method of modulating an immune response in an animal using such compositions.
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