Compounds, preparation process, and uses thereof used for interrupting reuptake of 5-hydroxytryptamine and norepinephrine or treating diseases such as depression et al.
Compounds of the general formula (I), optical isomers, pharmaceutically acceptable salts,preparation process and uses thereof in which R1, R2, R3 and R4 are as defined inspecification are disclosed. Such compounds can be optical isomers or racemic mixturesand can be metabolically transformated into 1-[2-dimethylamine-1-(4-hydroxyphenyl)-ethyl]cyclohexanol withnew pharmaceutically active in vivo after administration, which can be usedfor treating diseases associated central nervous system such as depression etal. by interrupting reuptake of 5-hydroxytryptamine (5-HT ) and norepinephrine (NA) .
