The Research Foundation for Microbial Diseases of Osaka University;Japan as Represented by the Director-General of National Inst. of Infectious Diseases
发明人:
Asato KOJIMA,Hidehiro TAKAHASHI,Toyokazu ISHIKAWA
申请号：
US14070948
公开号：
US20140065180A1
申请日:
2013.11.04
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the VLP secretion expression vector as an active ingredient.
