Konstantin Zhernosekov;Sebastian Marx;Mark Harfensteller;Tuomo Nikula
发明人:
Sebastian Marx,Mark Harfensteller,Konstantin Zhernosekov,Tuomo Nikula
申请号：
US14232205
公开号：
US20140294700A1
申请日:
2012.04.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a column chromatographic method of manufacturing non-carrier-added high-purity 177Lu compounds for medicinal purposes. In the method in accordance with the invention a cation exchanger and a suitable chelating agent are used. With the method in accordance with the invention it is possible for the first time to provide non-carrier-added high-purity 177Lu compounds in milligram amounts for pharmaceutical-medicinal purposes from 176Yb compounds irradiated with thermal neutrons, the radionuclides 177Lu and 176Yb being present in an approximate mass ratio of 1:102 to 1:1010 for purification.
