PROBLEM TO BE SOLVED: To provide a method for producing a solid preparation substrate which can simply improve a durability of printing pictures formed on the surface of a solid preparation by an ink-jet method even if a dye stuff is used as an aqueous ink for ink jet printing, and to provide a solid preparation substrate generated by the producing method concerned.SOLUTION: An image is printed on a surface of solid preparations using aqueous ink comprising an aqueous solvent with a high-boiling point by an ink jet printing method, and heating preservation treatment is performed after the printing. According to the method for producing the above-mentioned solid preparation substrate, because the heating preservation treatment is performed in a condition that an ink flowability is improved without completely drying the printing image immediately after printing, an effect that ink adhered on the surface of the solid preparation permeates inside the solid preparation during the heating preservation treatment is acquired, and a durability of the printed image can be improved by becoming difficult to subject to the influence of light from outside or humidity directly.COPYRIGHT: (C)2015,JPO&INPIT