CHUNTHARAPAI, ANAN,KIM, JIN K.,PRESTA, LEONARD G.,STEWART, TIMOTHY
申请号：
CA2437161
公开号：
CA2437161C
申请日:
2002.01.29
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates generally to the generation and characterizationof neutralizing anti-IFN-.alpha. monoclonal antibodies with broad reactivityagainst various IFN-.alpha. subtypes. The invention further relates to the useof such anti-IFN-.alpha. antibodies in the diagnosis and treatment ofdisorders associated with increased expression of IFN-.alpha., in particular,autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) andsystemic lupus erythematosus (SLE).
