Compounds Derivatives of 2 - amino - 4 - (pyridin-2-yl) - 5.6 - dihydro - 4 - 1.3 - oxazine； Composition and Pharmaceutical Combination； and use in the Treatment or prevention of Alzheimer's disease, Type 2 diabetes, obesity, and other diseases.
RAINER MARTIN LUEOEND,RAINER MACHAUER,HEINRICH RUEEGER,SIEM JACOB VEENSTRA
申请号：
CL2014000458
公开号：
CL2014000458A1
申请日:
2014.02.25
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The invention relates to novel oxazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease via inhibition of BACE-1.COMPUESTOS DERIVADOS DE 2-AMINO-4-(PIRIDIN-2-IL)-5,6-DIHIDRO-4H-1,3-OXAZINA INHIBIDORES DE BACE-1 Y BASE-2； COMPOSICION FARMACEUTICA QUE LOS COMPRENDE； UTILES EN EL TRATAMIENTO O PREVENCION DE LA ENFERMEDAD DE ALZHEIMER, DETERIORO COGNITIVO LEVE, DIABETES TIPO 2, OBESIDAD, HIPERTENSION, ENTRE OTRAS.
