DORFMAN ADAM R U S A,BRYCE DAVID A U S A,GRACE MAXWELL A U S A,PIERCE D KYLE U S A,MERZLIAKOV MIKHAIL U S A,MORTENSON MARK G U S A
申请号：
IN3062/KOLNP/2013
公开号：
IN2013KN03062A
申请日:
2013.10.21
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
The present invention relates to novel gold- platinum based bi-metallic nanocrystal suspensions that have nanocrystal surfaces that are substantially free from organic or other impurities or films associated with typical chemical reductants/stabilizers and/or raw materials used in nanoparticle formation processes. Specifically, the surfaces are "clean" relative to the surfaces of metal based nanoparticles made using chemical reduction (and other) processes that require organic (or other) reductants and/or surfactants to grow (and/or suspend) metal nanoparticles from metal ions in a solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the bi- metallic nanocrystal suspensions. The techniques do not require the use or presence of chlorine ions/atoms and/or chlorides or chlorine based materials for the manufacturing process/final suspension. The invention further includes pharmaceutical compositions thereof and the use of the bi-metallic nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which metal-based therapy is already known, including, for example, for cancerous diseases or conditions.
