THE GENERAL HOSPITAL CORPORATION DBA MASSACHUSETTS GENERAL HOSPITAL;NOVARTIS AG
发明人:
DARDAEI ALGHALANDIS, LEILA,ENGELMAN, JEFFREY ADAM,HAO, HUAIXIANG,LI, FANG,LAMARCHE, MATTHEW J.,WANG, HUI-QIN
申请号:
CA3048340
公开号:
CA3048340A1
申请日:
2018.01.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
A pharmaceutical combination comprising an ALK inhibitor, in free form or a pharmaceutically acceptable salt thereof, and a SHP2 inhibitor, in free form or a pharmaceutically acceptable salt thereof, and optionally a pharmaceutically acceptable carrier, for simultaneous or sequential administration; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.