The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the Serpinc1 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of Serpinc1 and to treat subjects having a Serpinc1-associated disease, e.g., a bleeding disorder, such as a hemophilia.本發明係有關一種靶向Serpinc1基因之iRNA(例如,雙股核糖核酸(dsRNA))組成物,及使用此等iRNA(例如,dsRNA)組成物抑制Serpinc1表現及治療罹患Serpinc1-相關疾患(例如,出血疾患,如血友病)之個體之方法。由於本案的圖為實驗結果數據圖,並非本案的代表圖。故本案無指定代表圖。
