A COMBINATION OF OXYCODONE AND NALOXONE FOR USE IN TREATING PAIN IN PATIENTS SUFFERING FROM PAIN AND A DISEASE RESULTING IN INTESTINAL DYSBIOSIS AND/OR INCREASING THE RISK FOR INTESTINAL BACTERIAL TRANSLOCATION
VON COBURG, YVONNE,REIMER, KAREN,OKSCHE, ALEXANDER,HOLZER, PETER
申请号：
PH12016500063
公开号：
PH12016500063A1
申请日:
2016.01.08
申请国别(地区):
PH
年份:
2016
代理人:
摘要：
The present invention is concerned with an oral pharmaceutical dosage form comprising oxycodone or a pharmaceutically acceptable salt thereof and naloxone or a pharmaceutically acceptable salt thereof for use in the treatment of pain in patients suffering from i) pain and at least one further disease ii), wherein said at least one further disease ii) results in intestinal dysbiosis, or for use in the treatment of pain in patients suffering from i) pain and at least one further disease iii), wherein said at least one further disease iii) increases the risk for intestinal bacterial translocation and thus for peritonitis, SIRS and/or sepsis.
