An endoscopic surgical instrument including a fluid jet device and an electrode device. The fluid jet device includes a pipe section with a nozzle on one distal end for a dissection and/or a needleless injection by means of a fluid and the electrode device is for cutting and/or coagulating tissue, the pipe section forming the electrode device. The surgical instrument further includes an insulating device attached to the distal end of the pipe section such that the tissue can only be brought into electrically conductive contact with a peripheral region of the pipe section and not with the distal end of the pipe section.