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NOUVEAU DÉRIVÉ DE L'ANILINE, COMPOSITION PHARMACEUTIQUE LE CONTENANT, ET SON UTILISATION
专利权人:
Kissei Pharmaceutical Co.; Ltd.
发明人:
申请号:
EP15755976.6
公开号:
EP3112347A1
申请日:
2015.02.27
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
[Problem] The present invention provides a novel compound having an S1P1 receptor antagonistic activity.[Solution] The present invention provides a compound represented by the general formula (I): (in the formula, R1, R2 and R3 are each a hydrogen atom, a halogen atom, a C1-6 alkyl group, a halo C1-6 alkyl group or the like, R4 is a C1-6 alkyl group or the like, R5 is a C1-6 alkyl group or the like, R6 is a C1-6 alkyl group or the like, R7 is a hydrogen atom, a halogen atom, a C1-6 alkyl group or the like, R8 is a halogen atom, a C1-6 alkyl group, a halo C1-6 alkyl group, a C1-6 alkoxy group or the like, and R9 is a hydrogen atom or a C1-6 alkyl group.) or a pharmaceutically acceptable salt thereof, a pharmaceutical compositions containing same, and use thereof. The compounds of the present invention have an excellent SIP1 receptor antagonistic activitiy and therefore are useful as an agent for the treatment or prevention of antoimmune diseases and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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